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pentobarbital will reduce the level or effect of conjugated estrogens by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.pentobarbital will increase effects of ifosfamide by impacting hepatic enzyme CYP2B6 metabolism. Use Warning/Observe. Coadministration of ifosfamide with CYP2B6 inducers might enhance metabolism of ifos